Acetone is a colorless, flammable liquid that is often used as a solvent in industry and as a nail polish remover. In medicine, acetone is primarily known for its role in the production of ketone bodies, which are molecules produced in the liver from fatty acids during times of fasting or low carbohydrate intake.
Acetone is one of three ketone bodies produced by the liver, along with acetoacetate and beta-hydroxybutyrate. When the body produces high levels of ketone bodies, including acetone, it is known as ketosis. Ketosis can occur in a variety of situations, including during fasting, low-carbohydrate diets, and in people with diabetes who do not have enough insulin to use glucose for energy.
In medicine, acetone can be measured in the breath, blood, and urine to diagnose and monitor conditions such as diabetes and certain metabolic disorders. For example, people with diabetes who are experiencing diabetic ketoacidosis, a serious complication of diabetes in which high levels of ketone bodies, including acetone, accumulate in the blood, can have their acetone levels measured to help diagnose the condition and monitor its treatment.
In addition to its role in the production of ketone bodies, acetone can also be used as a diagnostic tool for other conditions. For example, acetone breath tests can be used to diagnose certain gastrointestinal conditions, such as small intestinal bacterial overgrowth.
Overall, acetone is a colorless, flammable liquid that is primarily known for its role in the production of ketone bodies, which are molecules produced in the liver from fatty acids during times of fasting or low carbohydrate intake. Acetone can be measured in the breath, blood, and urine to diagnose and monitor certain conditions, and can also be used as a diagnostic tool for other conditions.