Additive genetic effects refer to the contribution of multiple genes to a particular trait or disease. These effects occur when the combined influence of multiple genes, each with a small effect, adds up to a significant effect on the trait or disease.
In human genetics, additive genetic effects can be studied using methods such as genome-wide association studies (GWAS) and heritability analysis. GWAS identify genetic variants associated with a particular trait or disease, while heritability analysis estimates the proportion of variance in a trait that can be attributed to genetic factors.
Additive genetic effects can also be influenced by environmental factors, which can interact with genetic factors to affect the expression of a particular trait or disease. The study of gene-environment interactions is an important area of research in human genetics, as it can provide insights into the complex interplay between genetic and environmental factors in the development of diseases and traits.
