Adipose most abundant gene transcript 1 (Adig or Adm1) is a gene that codes for a protein hormone called adropin. Adropin is a small peptide hormone that is predominantly produced in the liver and brain, but is also expressed in adipose tissue and other organs.
Adropin has been found to play a role in regulating glucose and lipid metabolism, energy homeostasis, and insulin sensitivity. It also has neuroprotective properties and has been shown to improve cognitive function in animal models.
Research has suggested that adropin may be a potential therapeutic target for the treatment of metabolic disorders, such as obesity, type 2 diabetes, and cardiovascular disease. Studies in animal models have shown that administration of adropin can improve glucose tolerance, reduce adiposity, and improve lipid profiles.
Human studies have also shown a correlation between low adropin levels and metabolic disorders, such as insulin resistance and obesity. However, further research is needed to determine the clinical relevance of adropin and its potential as a therapeutic target.
In summary, Adig or Adm1 is a gene that codes for a protein hormone called adropin, which plays a role in regulating glucose and lipid metabolism, energy homeostasis, and insulin sensitivity. Adropin may be a potential therapeutic target for the treatment of metabolic disorders, but more research is needed to determine its clinical relevance.
