In medicine, AFAP stands for “Attenuated Familial Adenomatous Polyposis.” This is a rare, inherited condition that increases a person’s risk of developing colorectal cancer. AFAP is caused by mutations in the adenomatous polyposis coli (APC) gene, which normally functions to suppress the growth of polyps in the colon.
People with AFAP typically develop fewer polyps than those with the more common condition called Familial Adenomatous Polyposis (FAP), but they still have a higher risk of developing colorectal cancer than the general population. The symptoms of AFAP are similar to those of FAP and include abdominal pain, diarrhea, and bleeding from the rectum.
Screening for AFAP typically involves colonoscopies and genetic testing to identify mutations in the APC gene. Treatment may include regular surveillance and removal of polyps to reduce the risk of cancer, as well as preventative measures such as a healthy diet and exercise.
