Calcipotriene is a medication used to treat psoriasis, a chronic skin condition that causes red, scaly patches on the skin. It is a synthetic form of vitamin D3, also known as calcitriol, that works by regulating the growth and differentiation of skin cells. Calcipotriene is available in the form of a cream, ointment, or solution that is applied directly to the affected areas of the skin.
Calcipotriene is typically used to treat mild to moderate psoriasis, although it may also be used in combination with other medications for more severe cases. It is generally well-tolerated and has fewer side effects than other psoriasis treatments such as corticosteroids. However, like any medication, it may cause side effects such as skin irritation, burning, or itching at the site of application.
Calcipotriene should not be used in individuals with a history of hypersensitivity to vitamin D or any of its derivatives. It should also be used with caution in individuals with severe renal impairment, as high levels of vitamin D may lead to hypercalcemia (elevated levels of calcium in the blood). In addition, patients taking calcipotriene should avoid excessive exposure to natural or artificial sunlight, as this can increase the risk of skin irritation or burning.
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