Diseases

Leigh syndrome, first described by Denis Leigh in 1951, is a severe progressive neurometabolic disorder characterized by bilateral symmetric necrotic lesions in subcortical regions of the central nervous system. Originally termed subacute necrotizing encephalomyelopathy, this disorder represents a final common phenotype for various genetic defects affecting energy metabolism.

The landscape of eczema treatment is rapidly evolving, with groundbreaking research and innovative therapies offering new hope for patients with this challenging condition. Scientists and medical researchers are making significant strides in understanding the complex mechanisms behind eczema, leading to the development of more targeted and effective treatments. These advances promise to revolutionize how we approach eczema management in the coming years.

The relationship between asthma and eczema is more than just a coincidence - it's part of a larger pattern known as the atopic march. This progression of allergic conditions often begins in early childhood with eczema and can lead to the development of food allergies, allergic rhinitis (hay fever), and asthma. Understanding this connection is crucial for both prevention and management of these related conditions.

Dyshidrotic eczema, also known as pompholyx or vesicular eczema, is a distinctive form of eczema that affects the hands and feet. This challenging condition is characterized by small, intensely itchy blisters that can cause significant discomfort and impact daily activities. Understanding this specific type of eczema is crucial for effective management and treatment.

When over-the-counter treatments prove insufficient for managing severe eczema, prescription medications become a necessary step in achieving better symptom control. Understanding the various prescription options available, their benefits, and potential side effects is crucial for making informed decisions about treatment in partnership with healthcare providers. This comprehensive guide explores the main categories of prescription medications used in treating severe eczema.

West Syndrome, also known as infantile spasms, is a rare but severe form of age-dependent epileptic encephalopathy that typically manifests in infancy. This devastating condition is characterized by the triad of infantile spasms, hypsarrhythmia on EEG, and developmental regression. Early recognition and prompt intervention are crucial for optimizing outcomes in affected infants.

Living with eczema can be challenging, and many people don't realize that the air quality in their homes plays a crucial role in managing this chronic skin condition. The amount of moisture in the air, known as humidity, can significantly impact eczema symptoms and overall skin health.

Eczema in the elderly presents unique challenges due to aging skin and often complex medical histories. The condition requires specialized attention and care strategies that take into account the natural changes in skin structure, slower healing processes, and potential complications that can arise in older adults.

Living with eczema extends far beyond managing physical symptoms, as the condition can have profound effects on mental health and emotional well-being. The visible nature of eczema, combined with persistent discomfort and unpredictable flare-ups, can create significant psychological challenges that require attention and support.

A detailed clinical review of cerebral palsy covering classification, pathophysiology, diagnosis, management, and outcomes for healthcare professionals and medical students.

A detailed clinical guide on acute rheumatic fever covering pathophysiology, diagnosis, treatment, and prevention strategies for medical professionals and students.

Henoch-Schönlein Purpura (HSP), now termed IgA Vasculitis, is the most common systemic vasculitis in children. It is characterized by IgA-mediated small vessel vasculitis affecting the skin, gastrointestinal tract, joints, and kidneys. This comprehensive review provides medical professionals with current evidence-based information on the pathogenesis, clinical manifestations, and management of HSP.

Scabies is a highly contagious parasitic skin infestation caused by the mite Sarcoptes scabiei var. hominis. This microscopic ectoparasite burrows into the epidermis, causing intense pruritus and characteristic skin lesions. This comprehensive review provides medical professionals with current evidence-based information on the diagnosis, management, and prevention of scabies infestations.

Ichthyosis comprises a group of genetic skin disorders characterized by widespread and persistent scaling of the skin. The condition, derived from the Greek word "ichthys" meaning fish, refers to the fish-scale-like appearance of the affected skin. This comprehensive review provides medical professionals with current understanding of the pathogenesis, classification, and management strategies for ichthyosis disorders.

Eczema around the eyes presents a particularly challenging condition due to the delicate nature of the periorbital area and the significant impact it can have on both appearance and quality of life. Understanding how to properly care for this sensitive area while effectively managing symptoms requires specific knowledge about safe treatment methods and appropriate products.

Understanding the distinction between scalp eczema and dandruff is crucial for effective treatment and management of these common scalp conditions. While both conditions can cause flaking and itching of the scalp, they have different underlying causes, symptoms, and treatment approaches that require specific attention and care strategies.