Energy metabolism

Monosaccharides are the simplest carbohydrates, serving as fundamental building blocks for more complex sugars and playing essential roles in biological processes. This image illustrates the structures of five key monosaccharides—glucose, fructose, galactose, deoxyribose, and ribose—divided into hexoses and pentoses, providing a clear visual guide to their molecular configurations. Exploring these molecules offers valuable insights into their metabolic significance and structural diversity in living organisms.

Leigh syndrome, first described by Denis Leigh in 1951, is a severe progressive neurometabolic disorder characterized by bilateral symmetric necrotic lesions in subcortical regions of the central nervous system. Originally termed subacute necrotizing encephalomyelopathy, this disorder represents a final common phenotype for various genetic defects affecting energy metabolism.