nucleosomes

The intricate organization of DNA within our cells is a fascinating topic in molecular biology. DNA macrostructure refers to the way DNA is meticulously packaged into higher-order structures to fit within the nucleus while remaining accessible for cellular processes like replication and gene expression. This article delves into the hierarchical organization of DNA, from its double helix form to the tightly packed chromosomes, with a focus on the roles of histones, nucleosomes, chromatin, and chromosomes. Through a detailed exploration of a medical diagram, we uncover how these components work together to ensure the stability and functionality of our genetic material.