Genetic Factors

Neural tube defects (NTDs) are serious birth defects of the brain, spine, or spinal cord. They occur during the first month of pregnancy, often before a woman even knows she's pregnant. The neural tube is the embryonic structure that eventually develops into the baby's brain and spinal cord and the tissues that enclose them. When this tube does not close completely, it results in neural tube defects.

Prune Belly Syndrome (PBS), also known as Eagle-Barrett syndrome, is a rare congenital disorder characterized by a triad of abnormalities: deficient development of the...